Flow Cytometry Service

Flow Cytometery Service

“The high-performance flow cytometer designed to support routine clinical assays and with exceptional consistency and standardization”.

 

“The flow crossmatch market may be one of the smallest, but standardization has the potential to have one of the greatest clinical impacts. It’s the little things that make a big difference in healthcare.”

– Dr. Robert Bray, Emory University, Atlanta, GA

 

Introduction

  • Flow cytometry is a widely used method for analyzing the expression of cell surface and intracellular molecules, characterizing and defining different cell types in a heterogeneous cell population, assessing the purity of isolated subpopulations and analyzing cell size and volume.
  • It is predominantly used to measure fluorescence intensity produced by fluorescent-labeled antibodies detecting proteins, or ligands that bind to specific cell-associated molecules.

 

The Advantages

  • A single sample, no matter how rare, can show an essential difference.
  • Multicolor analysis provides more answers from a single tube and decreases cost by reducing the number of tubes and reagents required to reach a diagnosis.
  • Runs at rates up to 35,000 events per second, sample carryover ≤ 0.05%.
  • Acquires a large number of events rapidly; useful for rare populations.
  • There is no limit on events acquired.
  • Outstanding resolution at all flow rates.
  • Enables faster detection without compromising quality.
  • Improvement in stain index of 8-190% across all parameters.
  • Better separation enables faster analysis and easier gating.
  • Higher sensitivity makes dim and rare populations easier to resolve.

 

What benefit to Our Clinician

  • This next-generation flow cytometer enables standardization and collaboration through consistent results and unique assay portability and sharing capabilities.
  • Its standardization helps maximize compatibility, interoperability, repeatability and quality that will enable you to maximize clinical performance and ensure accurate as well as reliable results.
  • It has high-performance, highly sensitive flow cytometer excels at assays with dim or rare cell populations, and is available in multiple configurations for flexibility that can adapt to your changing clinical needs.

 

Intended Used

Our Flow Cytometry Service is intended for immunophenotyping using up to 6 colours, and is useful in the diagnosis and monitoring of:

  • Acute & Chronic Leukemia,
  • Myelodysplastic Syndrome (MDS),
  • Lymphoproliferation,
  • Plasma cell disorders
  • and Paroxysmal nocturnal hemoglobinuria (PNH).

 

References:

  1. FACSLyric Flow Cytometer Brochure
  2. https://www.accessdata.fda.gov/cdrh_docs/reviews/K170974.pdf

The new normal in the workplace

The new normal in the workplace

Here are some tips on how to help prevent the spread of Covid-19 in your workplace:

  1. If you feel sick, go home
    • Do not stay at your workplace when you are not feeling well. If you prefer to stay, you should avoid touching people, surfaces and objects should cover your mouth with a disposable tissue when you cough or sneeze and throw the tissue in the bin.
  2. Keep physical distance but maintain social connection
    • Keeping space between you and others is one of the best tools we have to avoid being exposed to Covid-19. Limit close contact with others outside your household in indoor and outdoor spaces.
  3. Use video conferencing and phone calls as much as possible
    • Reduce face-to-face meeting with clients. Meetings can still take place where social distancing can occur.
  4. Workshop and training should be conducted online
    • Learning must not stop with Covid-19. Training can be done in virtual platform to reduce the social connection with others.
  5. Wash hands or use hand sanitizer often
    • Washing hands with soap and water whenever possible because handwashing reduces the amounts of all types of germs and chemicals on hands.
  6. Clean and disinfect high-touch surfaces regularly
    • Clean and disinfect high-touch surfaces every day, even if they are not visibly dirty. If they become visibly dirty, clean the surfaces. Wash frequently touched surfaces with a clean, reusable cloth or a disposable towel dipped in detergent and warm water.
  7. Return home early after work
    • Avoid happy hours, club activities, and other small group gatherings after work.

Tips for a healthy Ramadhan

Tips for a healthy Ramadhan

  1. Don’t miss sahur – Having sahur is essential to power up your body for the day.
  2. Fast, not feast – Avoid overeating when you break fast during Iftar as it is counter-productive for your body and can lead to weight gain.
  3. Stay fit – Whether you choose to do your workout before or after breaking fast, try to do low – to moderate intensity exercises to maintain your overall health.
  4. Break fast with dates and water – Dates not only provide a burst of energy, they are easily digested, rich in fibre, vitamins, minerals and helps prevent constipation.
  5. Avoid caffeine and sugary drinks – Avoid caffeine-based beverages such as tea, coffee or soda as these stimulate faster water loss through urination.
  6. Avoid simple sugars – Avoid white rice, white bread and desserts as these digests rapidly causing your blood sugar to drop quickly and leave you feeling hungry.
  7. Have a balanced meal – Half your plate with fruits and veggies, ¼ protein, and ¼ carbs.
  8. Include complex carbohydrates and fibre rich foods – Choose wholegrain pita bread or tortillas, oats, chia seeds, beans and brown rice.
  9. Don’t miss out on sleep – Get adequate sleep to sustain you throughout the day.

Stay physically active and calm during self-quarantine

Stay physically active and calm during self-quarantine

WHO recommends 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity physical activity per week, or a combination of both. These recommendations can still be achieved even at home, with no special equipment and with limited space. The following are some tips on how to stay active and reduce sedentary behaviour while at home in self-quarantine:

1. Take short active breaks during the day. Quick physical activity add up to the weekly recommendations. You may use the suggested exercises below as inspiration to be active every day. Dancing, playing with children, and performing domestic chores such as cleaning and gardening are other ways of remaining active at home.

2. Join the exercise class online. Take advantage of the variety of online exercise classes. Many of these are free and can be found on YouTube. If you have no experience performing these exercises, be cautious and aware of your own limits.

3. Start walking. Even in small spaces, walking around or on the spot exercise will help you stay active and healthy. When you have a call, instead of sitting down, stand or walk around your house while you are talking. If you decide to go outside for walking or exercise, make sure to maintain a distance of at least 1 meter from others.

4. Stand up. Reduce your sedentary time by standing up whenever possible. Ideally, aim to interrupt sitting and reclining time every 30 minutes. Consider setting up a standing desk to continue working while standing by using a high table or piling a pile of books or other materials. Prioritize cognitively stimulating behaviors during sedentary leisure time, such as reading, board games and puzzles.

5. Relax. Meditation and deep breaths can help you remain calm.

It is also important to keep eating healthily and stay hydrated. WHO recommends drinking water, rather than sugar-sweetened beverages. Limit or avoid alcoholic beverages for adults and strictly avoid these in young people, pregnant and breastfeeding women, or for other health reasons. Ensure plenty of fruits and vegetables, and limit the intake of salt, sugar and fat. Prefer whole grains instead of refined foods.

 

Warning:
This guidance is intended for people in self-quarantine without any symptoms or diagnosis
of acute respiratory illness. It should not replace medical guidance in case of any health condition.

 

Source: World Health Organization (WHO)