Facts about Tuberculosis (TB)

  • An airborne, highly contagious, infectious disease caused by the bacteria Mycobacterium tuberculosis.
  • In Malaysia, 26,168 new TB cases were reported in 2017 (2).

What is latent TB infection (LTBI)?

  • LTBI refers to a person’s exposure to the M. tuberculosis bacterium but they do not show any signs or symptoms of TB disease.
  • It is not contagious, and people can carry it for a very long period until it converts into an active, contagious form of the disease.
  • Treatment of LTBI can prevent conversion into an active form.

Treating LTBI prevents active TB

  • Identification and treatment of LTBI can substantially reduce the risk of development of active disease by as much as 60% (3).

Get yourself checked

Contact investigation may involve:

  • Clinical assessment
  • Chest radiography
  • Tuberculin skin test (TST)
  • Interferon-γ release assay (IGRA).

The modern IGRA blood test –> QuantiFERON®-TB Gold Plus (QFT®-Plus)

  • Easy to administer
  • Provides accurate and quick results.
  • Approved by the World’s Health Organization Model list of Essential In Vitro Diagnostics (1).



  1. World Health Organization. (2018) World Health Organization Model List of Essential In Vitro Diagnostics.
  2. Global Tuberculosis Report 2018 http://www.who.int/tb/publications/global_report/en/
  3. Kim, H. W., & Kim, J. S. (2018). Treatment of Latent Tuberculosis Infection and Its Clinical Efficacy. Tuberculosis and respiratory diseases, 81(1), 6-12. doi:10.4046/trd.2017.0052

Leave a Reply

Your email address will not be published.

You may use these <abbr title="HyperText Markup Language">HTML</abbr> tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>