2014: Re-evaluating the Significant of HPV DNA Test as a Primary Screening Test for Cervical Cancer.

Georgios Papanikolaou must be shock to hear this. The routine Pap Smear Test that he invented in 1928 will no longer play a crucial role in screening for cervical cancer. Early this year, U.S. Food and Drug Administration (FDA) panel of 13 members has voted unanimously to replace the conventional Pap Smear test with a new advanced Human Papillomavirus (HPV) DNA test as the standard acheter du cialis en ligne of care for American women.

The 13-0 votes-by a committee mainly of academic pathologists, microbiologists and gynecologists said that HPV Test is a vital test to detect the genetic material (DNA) of the virus in a sample of cells from the cervix and help identify women who may be at risk of cervical cancer. The advisory committee also recommended that the age for women to be offered an HPV Test be lowered from 30 to 25 years old.

The FDA is an agency of the U.S. Department of Health and Human Services who is responsible for approving laboratory tests before they can be marketed in the U.S. The agency often follows the advice of its advisory committee members- most of them are experts in the field of academic health centers, industry, community practice, and consumer advocates.

Most Cervical Cancers are caused by HPV, a sexually transmitted infection, in particular HPV strains 16 and 18. In Malaysia, Cervical Cancer is the 3rd most frequent cancer among women. About 50% of the cases were diagnosed between the ages of 35 and 55, which are the most economically productive years for women.

In Pantai Premier Pathology, the test simultaneously screens for not only HPV 16 and HPV 18, but also 12 other HPV strains that put women at high risk for Cervical Cancer. Contact us now for more info.

Eating out with Allergies

People with allergies quite naturally have a tough time eating outside of their houses. Consuming foods that contain allergens could bring about allergic reactions that range from mild, relatively harmless reactions to a dangerous life threatening situation.

Fret not, here are a few tips to ease those of you who have tendency to have an allergic reaction and wishes to eat out:

1. Be Informed

Get to know your allergies and the food you should avoid. Also be sure to know all the different type of names these foods can be called.

2. Speak Up.

Don’t be afraid to ask the waiter about the menu, and be sure to speak loud and clear while doing so. Trainee waiters and waitresses may not be prepared to answer your questions, and in this case, don’t hesitate to kindly ask to speak to the manager or a more senior member of the staff who could assist you.

3. Review Eating Places.

Nowadays, most restaurants post their menus online. This provides an easy avenue to check the menu and determining whether or not the eatery is a good choice for you.

4. Carry a ‘Chef Card’.

You can use a chef card to write a little note to the kitchen staff. Include the things you are allergic to, ingredients you have to avoid, and a little reminder that all utensils should be cleaned while preparing your meal.

5. Keep your medicines close.

You never know when an emergency will strike, so it is better to be safe than sorry. Carry your medicines at all times.

6. Allergy Bracelets.

These bracelets inform people about the type of allergy you are having, so that in the case of an emergency, due action can be taken.

7. Don’t Compromise.

Alert your friends beforehand about you allergies, and tell them the seriousness of your allergies. One of the most common problems is that friends often think serious allergic reactions like inability to breathe are just act of goofiness and merely just fooling around.This simple step could help save your life.

(Source: www.allergyeats.com)

Allergies During Pregnancy

About 25% of expectant mothers complain of some sort of allergic symptoms or the other during their pregnancies. It is quite common for pregnant women to get allergies during pregnancies. While some women with allergies before conceiving a child express that they undergo a dramatic hike in their allergic reactions during pregnancy, most of those with no allergies pre-pregnancy state that these reactions often only show up during pregnancy.

Now why does this happen?

Pregnancy is a period when the body of a woman undergoes many changes to facilitate a baby. One of the known changes are the presence of pregnancy hormones, which helps make sure the little human within a woman gets the right environment to grow and develop into a human being. However, these hormones can cause some side effects to the mother, included but not limited to inducing morning sickness and allergic reactions.

Although the more common allergic reaction –runny nose and itching- mostly only cause discomfort to the mother without any harm to the baby, an anaphylactic shock can seriously have harmful effects to the baby.

If you do have allergic reactions, it is advised that you meet with your doctor to ask what you should do and what you should avoid to curb the risk of undergoing anaphylactic shock.

Due to the changing environments in the body, pregnant women should always consult if the medications they take to manage allergies are safe for them, even those who took the medicine before pregnancy and experienced no side effects. The effect of medication to a woman during pregnancy may change due to the ever changing environment of the body itself. Also, it is not advised to start receiving allergic shots during pregnancy, because doing so can trigger huge changes in the already fluctuating body of a pregnant woman.

It is said that the best defense to allergies is  – good offence. Stay away from dusty areas, or areas which will logically contain more allergens that will otherwise trigger an allergic reaction. Consult your doctor to confirm safe methods of managing allergies, to ensure that the fetus isn’t harmed.

(Source: http://www.whattoexpect.com , http://allergies.about.com)

Stop Allergy Attack!

Do you know…

It is estimated that 30%-40% of the world’s population is affected by one or more allergic conditions? Currently, there is about 15%-20% of Malaysian population suffering from allergies and this figure is expected to increase to 50%, 10 years from now. While most allergies appear during the early years of childhood, they can also develop in any person at any age. Allergies are not inherited. Yet, there is no cure at the moment.

The best way to stop an allergic reaction is of course, we PREVENT it! However, this is not always easy. If you are allergic to certain food like eggs, fish, soy, peanuts and so on, you can always prevent the allergic reaction by avoiding consuming them (Unless you are not realizing on it). But when it comes to house dust mites or fungal spores, then it will be hard to spot and get rid of them.

Allergic reaction may come in many different ways. Some allergic reactions can come via direct skin contact from exposure to poisonous plants, animal dander, pollen and latex. Some reaction is caused by injection through bee sting and medication. Ingestion of few types of food such as orange, crab, shrimp, milk-cow and so on can also lead to allergic reaction. Other means of allergic reaction including inhalation of pollen, dust, animal dander, mold & mildew.

Urbanization has created massive environmental toxins such as smoke, chemicals and fumes exposing us to the risk of allergies. Physical agents like sunlight, humidity and haze have also contributed to the problem. Allergic problems will continue to escalate as air pollution and ambient temperature increase due to environmental and climate changes.

Symptoms of allergic reactions range from minor nuisances such as itches, sneezing and watery eyes to more acute cases like a fall in blood pressure or severe breathing difficulties. If your child is suspected of suffering from an allergy, an experienced doctor is necessary to conduct allergy tests and to analyze the result accurately.

By doing allergy test, it can help to pinpoint which substances you are allergic to. The Allergy ASEAN Panel applied in our lab composed of both food and inhalant allergens tested in a single panel. Patient’s blood will be tested to measure the specific IgE level in the serum.

How do we show our kidneys some love? We take care of them of course!

The National Health Service, UK outlines 5 simple lifestyle tips to take care of your kidneys.

Step 1: Stay hydrated.

Your urine can act as a good indicator as whether or not you are drinking enough water, it should be straw colored or paler. Any darker may be a sign of dehydration.

Step 2: Eat healthy.

Make sure you get a balanced diet, complete with sufficient amounts of vitamins and minerals. Eating a lot of salty and fatty foods should be avoided as it can bring complications in the long run.

Step 3: Don’t smoke or drink too much alcohol.

These two habits could lead to you accumulating more toxins in your body. This means your kidneys will have to work extra hard to remove these toxins from your body.

Step 4: Watch your blood pressure.

A simple, quick and painless blood pressure check can help you detect whether or not you have high blood pressure. High blood pressure which normally has no symptoms, can actually lead to kidney problems.

Step 5: Watch your weight.

Being too heavy raises your blood pressure, and this can put extra strain on your kidneys. Your BMI should be a good measure of whether or not your weight is healthy.

 

Pantai Premier Pathology hopes that you follow these simple steps in taking care of your kidneys. They are small but vital parts of your body that we think deserve your care and attention. We hope this message helps you care for yourself as much as we care for you.

(Source: National Health Service, UK & National Kidney Foundation, NKF)

Are your Kidneys OK?

Globally, more than 500 million individuals, or about one in ten general populations, have some form of Chronic Kidney Disease (CKD). CKD means a condition that damages one’s kidneys by decreasing the ability to keep one healthy by doing their functions.

Kidney is very important in filtrating body fluids for excretion. It’s also produces certain essential hormones such as erythroprotein which stimulate the bone marrow to produce red blood cells. Blood pressure regulator hormone, renin is also produced by kidney. Once the kidney cannot filter our body fluid, a protein call albumin can be found in our urine, a condition called “protein leak” and may lead to complications such as high blood pressure, anaemia, heart and blood vessel disease.

The most common causes of CKD are patients with diabetes, high blood pressure, glomerulonephritis (inflammatory diseases of the kidney), infections, kidney stone disease and others.

Kidney diseases are often silent. Many people are unaware that their kidneys are damaged until they have done a medical examination. These are some of the signs and symptoms, depending on the type of kidney disease:

  • Discomfort or burning sensation when passing urine
  • Passing blood in the urine
  • A change in the frequency of urination
  • Back pain (loin)
  • Frequent urination especially during the night
  • Swelling of the ankles
  • Persistent puffiness around the eyes, particularly in the morning.

If you are diabetic, having high blood pressure, smokers, obese or over 50 years of age, you are advice to go for screening. Simple laboratory tests can be done on small samples of blood and urine to assess kidney function and protein excretion in urine. Coupled with these, you are also advice to monitor your glucose and cholesterol level as it might closely relate to your present health status.

Advanced technology in Renal Function Test shows that the use of Cystatin C as a measurement of kidney function from blood could lead to better staging and risk classification of CKD. It will allow targeted management of the condition for better and safer prescribing of medications. Cystatin C, a new kidney function marker is FDA-approved for diagnostic use. Now, it is becoming more widely available and in some settings provides improved estimates of kidney function.

Kidney Disease is a silent killer! Signs and symptoms occur late in kidney disease. Screening tests are vital, especially if you are at high risk. The progression of kidney disease can be slowed or stopped if detected earlier.

(Source: National Kidney Foundation & Med. J. Malaysia, Vol. 66)

Love Your Kidney

Kidneys are bean-shaped organs which are found at the back of your abdominal cavity. Though people are normally born with two functioning kidneys, one on either side of the spine, a person can survive with only one kidney.

The kidney plays an important role as the natural filter in our body systems. In very simple terms, once the blood has entered our acheter viagra kidneys via the renal arteries, the kidneys will remove waste substances (such as urea) in the blood to be directed to the urinary bladder, and reabsorb useful substances (such as water) back into our body to be used. Most of this filtration process takes part in the nephron of the kidneys.

Other than filtering our blood, the kidney also makes sure the pH levels in our bodies are balanced. The kidney regulates the acid-base balance by reabsorbing bicarbonate ions from the urine and excreting hydrogen ions into urine. On top of that, the kidney regulates the osmotic pressure (also known as water pressure) in our bodies via reabsorption of water. Although the kidney cannot directly sense blood, it is important in maintaining blood pressure in our bodies. The kidneys are also involved in hormone secretion; it excretes erythropoietin in response to low oxygen levels in your blood, stimulates bone marrow production in the bone marrow and also secretes the enzyme; renin.

Isn’t it amazing how a small organ (about 13 cm long) plays such an important role to us?

(Source: National Health Service, UK & National Kidney Foundation, NKF)